Amitriptyline

Why is this medication prescribed?

Amitriptyline is used to treat symptoms of depression. Amitriptyline is in a class of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.

How should this medicine be used?

Amitriptyline comes as a tablet to take by mouth. It is usually taken one to four times a day. Take amitriptyline at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amitriptyline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of amitriptyline and gradually increase your dose.

It may take a few weeks or longer before you feel the full benefit of amitriptyline. Continue to take amitriptyline even if you feel well. Do not stop taking amitriptyline without talking to your doctor. If you suddenly stop taking amitriptyline, you may experience withdrawal symptoms such as nausea, headache, and lack of energy. Your doctor will probably decrease your dose gradually.


Other uses for this medicine

Amitriptyline is also used to treat eating disorders, post-herpetic neuralgia (the burning, stabbing pains, or aches that may last for months or years after a shingles infection), and to prevent migraine headaches. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.



What side effects can this medication cause?

Amitriptyline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea

  • vomiting

  • drowsiness

  • weakness or tiredness

  • nightmares

  • headaches

  • dry mouth

  • constipation

  • difficulty urinating

  • blurred vision

  • pain, burning, or tingling in the hands or feet

  • changes in sex drive or ability

  • excessive sweating

  • changes in appetite or weight

  • confusion

  • unsteadiness

Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

  • slow or difficult speech

  • dizziness or faintness

  • weakness or numbness of an arm or a leg

  • crushing chest pain

  • rapid, pounding, or irregular heartbeat

  • severe skin rash or hives

  • swelling of the face and tongue

  • yellowing of the skin or eyes

  • jaw, neck, and back muscle spasms

  • uncontrollable shaking of a part of the body

  • fainting

  • unusual bleeding or bruising

  • seizures

  • hallucinating (seeing things or hearing voices that do not exist)

Amitriptyline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.


http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000666/